Conversely, in ACC, KIRP, LGG, LIHC, and PRAD, KIAA1429 expression positively regulates the cell cycle, ECM receptor interaction, and tumor-related pathways, including P53, TGF-β, WNT, ERBB, and calcium signaling (Figure 5B). The gene discussed is TGFB1; the disease is adrenal cortex carcinoma.