CHMP2B and frontotemporal dementia: Compared to the localization profiles of CHMP2B with the T104N mutation in organelles, CHMP2B with mutations D148Y and Q165X (associated with the predominantly FTD phenotype) seemed unlikely to be localized in the Golgi body or in the ER and lysosome (see Figure S1), suggesting specific localization of CHMP2B with the T104N mutation (associated with the predominantly ALS phenotype) in the Golgi body.