For example, circTADA2As inhibit breast cancer progression and metastasis through targeted regulation of the miR-203A-3p/SOCS3 pathway.9 Another study showed that circRNA_103809 inhibits the proliferation and metastasis of breast cancer cells by regulating microRNA-532-3p.10 Although circRNA has been reported in breast cancer studies, the biological role of circRNA in breast cancer progression and metabolism has not been fully clarified. The gene discussed is SOCS3; the disease is breast carcinoma.