Subgroup analysis demonstrated that in the MetS (+) group, there was a positive relationship between increasing number of MetS components (i.e. the severity of MetS) and serum UA levels (4.81 ± 1.36 vs. 5.01 ± 1.46 vs. 5.09 ± 1.53, respectively, p < .001) as well as hs‐CRP levels (4.47 ± 8.71 vs. 5.40 ± 10.39 vs. 5.50 ± 8.11, respectively, p < .001). This evidence concerns the gene MAP3K14 and metabolic syndrome.