Then, by immunohistochemistry we analysed the protein levels of IKKβ, IKKα and p65 in human vascular samples (Figure 2) and confirmed a significant increase of IKKα, IKKβ and p65 in vascular samples from ACA in relation to CAs or subjects with early atherosclerosis (Figures 2A, 2B, 2C and 2D, respectively). Here, IKBKB is linked to atherosclerosis.