Meta-analysis results showed that the SENs of 18 F-PSMA-1007 PET/CT, 18 F-FDG PET/CT, and 68Ga-PSMA PET/CT were 0.912, 0.748, and 0.916, respectively, and the SPEs were 0.878, 0.639, and 0.734, respectively, suggesting that 18 F-PSMA-1007 PET/CT and 68Ga-PSMA PET/CT were superior to 18 F-FDG PET/CT in the diagnostic accuracy, and 68Ga-PSMA PET/CT showed higher sensitivity in the diagnosis of PCa. The gene discussed is FOLH1; the disease is posterior cortical atrophy.