During the hospitalization and subsequent follow-up, analyses in the laboratory indicated elevation in the levels of anti-beta-2 glycoprotein I (total anti-β2GPI = 19.1 U/ml [Normal range: < 16]), anticardiolipin (aCL IgG = 15.1 U/ml [Normal range: < 10U/ml]) IgG, Lupus Anticoagulant (LAC = 90 [Normal range: < 40]), erythrocyte sedimentation rate (ESR = 103 mm/hr), positive anti-nuclear antibody (ANA), anti-double-stranded DNA (ds-DNA) antibody, and hypocomplementemia were detected during thrombophilia screening (Table 1). The gene discussed is APOH; the disease is systemic lupus erythematosus.