On the follow-up examination and repeat of the laboratory test that showed anti-β2GPI IgG was 1.22, β2GPI IgM was 0.97, and aCL IgG was 2.64, the diagnosis of Lupus-associated APS was made, and the patient underwent regular follow-up (Fig. 3). The gene discussed is ACLY; the disease is systemic lupus erythematosus.