Conversely, pathways related to immune response and surveillance, tumor inhibition and apoptosis induction, and trail were significantly activated in the low-risk group (Fig. 7A) (such as Estrogen, JAK-STAT, NFκB, P53, TGFβ, TGFα); 2057 DEGs between the high- and low-risk groups, with 547 downregulated and 1510 upregulated (Fig. 7B). This evidence concerns the gene SOAT1 and neoplasm.