MAPK1 and nasopharyngeal carcinoma: Exosomal miRNA (hsa-miR-24-3p, hsa-miR-891a, hsa-miR-106a-5p, hsa-miR-20a-5p, and hsa-miR-1908) derived-nasopharyngeal carcinoma (NPC) mediate T-cell dysfunction by targeting the down-regulation of the MAPK1 and JAK/STAT pathways [69].