CD8A and infection: Given the differences in T-cell responses observed between SARS-CoV-2 naive and previously-infected healthcare workers pre- and post-omicron infection, as well as distinct patterns of response to spike and non-spike proteins, detailed phenotypic characterization of SARS-CoV-2 epitope-specific CD8+ T cells was performed using major histocompatibility complex (MHC) class I-peptide multimer staining and multi-parameter flow cytometry.