We observed the survival curves of LAMP family members in all cancers, and found that in all types of cancers, the high expression of LAMPs was most correlated with poor prognosis of LGG, among which, the high expression of LAMP1, LAMP2, and LAMP3 genes in LAMPs was significantly correlated with poor prognosis of LGG (Fig. 2B). The gene discussed is LAMP3; the disease is cancer.