SQSTM1 and Parkinson disease: This will result in increased mitochondrial ROS production in PD, which can lead to neurodegeneration, such as by increasing assembly of the neuronal NLRP3 inflammasome.[92] Thus, promoting mitophagy by inducing oligomerisation of p62 and potentially other SARs using small molecules, which are being developed for p62‐mediated autophagy,[48] could be a new strategy to treat these diseases which manifest mitochondrial dysfunction.[57]