RP2 and cancer: To explore the interaction between the pivotal gene and the available therapeutic agents for cancer, we used the CTD database to produce the interaction network between RP2 and drugs, and the results showed that cobaltous chloride and jinfukang were able to inhibit the gene expression of RP2, while six drugs or small molecules such as Methotrexate and Cisplatin were able to promote the expression of RP2 (Figure 12B).