Tusi et al. demonstrated that protein levels of two RAN translation reporters harboring myotonic dystrophy type 2 CCUG•CAGG repeats were markedly reduced in PERK KO cells, PKR KO cells, and eIF2A KO cells, as well as in eIF2α-S51A mutant cells (22). The gene discussed is EIF2AK2; the disease is Proximal myotonic myopathy.