For example, in gastric cancer, exosomal miR-130a and miR-155 secreted by gastric cancer cells can inhibit the expression of the transcription factor c-MYB, indirectly promoting the expression of VEGFA (Arcucci et al., 2021b), which promotes angiogenesis and further assists in invasion and metastasis of gastric cancer cells. This evidence concerns the gene MYB and gastric cancer.