Studies have shown that IFITM3 is involved in the inflammatory response of the central nervous system and plays a vital role in the pathogenesis of neurodevelopmental diseases related to immune activation, such as schizophrenia, Alzheimer disease, maternal infection virus and disrupting the normal development of the neonatal mouse brain (Ibi et al., 2009; Horvath and Mirnics, 2014; Hur et al., 2020). This evidence concerns the gene IFITM3 and schizophrenia.