Previously generated sCNV calls from the UK Biobank18,19 identified two persons without history of psychiatric disorder (of ∼500,000 individuals) with similar sCNV breakpoints affecting exons 1–5 in NRXN1. Although the arrays used in the UK Biobank have different sensitivity compared with arrays used in this study, they should have comparable sensitivity to detect these large events at CF > 10%.18 Here, NRXN1 is linked to psychiatric disorder.