XPO1 plays a number of key roles of relevance in MM [29] (Figure 1); in addition to exporting TSPs and cell cycle regulators, XPO1 exports immune response regulators such as IκB, the inhibitor of the transcription factor nuclear factor‐κB (NF‐kB), leading to dysregulated cellular growth signalling and an anti‐apoptotic state. The gene discussed is XPO1; the disease is Miyoshi myopathy.