Study has assessed inflammatory biomarkers in this population, as in steady state as in crisis, and in healthy controls, and have observed higher levels of TNF‐α in Hb‐SS individuals compared to Hb‐AA, as well as in Hb‐SS individuals in steady state in relation to those in crisis, which corroborates the current findings and the presence of chronic inflammation in SCA [11]. The gene discussed is TNF; the disease is autosomal dominant cerebellar ataxia.