IFNA1 and neoplasm: Radiation can promote the release of damage-associated molecular patterns (DAMPs) and tumor antigens via immunogenic cell death, activate the production of type I interferon (IFN) and IFN-stimulated genes via DNA damage that is sensed via the cGAS/STING pathway, and activate antigen-presenting cells, including dendritic cells (DCs) and macrophages (53).