We also uncover a highly specific transcriptomic signature of miR-16/miR-519-dysregulated genes, enriched in cell cycle genes and HuR targets, and confirmed on external datasets of human meningiomas, suggesting that the putative tumor suppressor effect of these miRs is mediated, at least in part, via HuR direct or indirect inhibition. Here, ELAVL1 is linked to meningioma.