GSD Type I or Von Gierke disease, also known as Glucose-6-phosphate deficiency. GSD Type 1a (GSD1a) glucose-6-phosphatase (G6Pase) deficiency (encoded by G6PC). Type 1b and 1c (GSD1b or 1c) glucose-6-phosphate translocase (G6PT) deficiency (encoded by SLC37A4). This evidence concerns the gene G6PC1 and autoimmune type 1 diabetes.