HIF1A and glioblastoma: This may be occurring by inducing alteration in other pathways, such as cell cycle regulation via the Forkhead box protein O1 (FOXO1) pathway in ovarian cancer (56), intracellular glycogen degradation by hypoxia-inducible factor 1-alpha (HIF1α) and signal transducer and activator of transcription 3 (STAT3) in glioblastoma (57), and by regulating the activation of PI3K/AKT/mTOR pathway in cervical cancer (58).