Yang et al. (2019) revealed that miR-155 was down-regulated in spinal tuberculosis and could potentially mediate disc destruction by regulating the expression levels of related proteins in the intervertebral disc through up-regulating MMP13 expression. Liang et al. (2023) successfully developed a diagnostic model based on a 3-plasma miRNA biomarker signature (hsa-miR-506-3p, hsa-miR 543, hsa-miR-195-5p) and suggested its potential use in differentiating spinal tuberculosis from other spinal destructive diseases and tuberculosis. This evidence concerns the gene MMP13 and tuberculosis, spinal.