Much effort has since been made to further understand the influence of mTOR on epileptogenesis and related processes Inhibiting mTOR through rapamycin pretreatment rescued the reduced distal dendritic branching and spine density observed following pilocarpine induced status epilepticus, though the effect in higher order branches was unable to be determined due to extensive loss (Brewster et al., 2013). This evidence concerns the gene MTOR and status epilepticus.