Furthermore, a very unusual PTM, the deamidation at asparagine (Asn37, Asn106, Asn207, Asn214, and Asn239) and glutamine (Gln166 and Gln226) of VDAC1 was discovered in response to oxidative stress and known to interact with superoxide dismutase1 (SOD1) mutant (SOD1G93A) in NSC34 cells of amyotrophic lateral sclerosis (ALS) (Pittalà et al., 2020). This evidence concerns the gene VDAC1 and amyotrophic lateral sclerosis.