ACE2 and infection: Furthermore, RNAseq data analysis of A549 and Calu-3 cells infected with SARS-CoV-2 for 24 h showed that epithelial cell adhesion molecules (EPCAM) gene expression was downregulated in epithelial cells, and ZEB1 was upregulated in Calu-3, A549, and A549 + ACE2 cell lines after infection.