For future clinical trials of NecroX-7 in epilepsy, it will be valuable to compare the therapeutic efficacies of multiple drugs that can regulate various aspects of necroptosis, i.e., necrostatin-1 (Nec-1), dabrafenib, or necrosulfonamide (NSA), with respect to that of NecroX-7. This evidence concerns the gene PCSK1 and epilepsy.