KITLG and anemia: A role for SNAI2 downstream of SCF/cKIT signaling in HSCs was postulated based on similar phenotypes observed between Snai2 KO mice and cKit or Scf mutant mice, supported by data showing induction of Snai2 expression upon Scf stimulation of cKit in vitro and anemia-induced activation of cKit signaling in vivo (72).