Furthermore, knockdown of AC016773.2, AC024060.2, and AC026401.3 inhibited cell proliferation, migration, and invasion, suggesting that these lncRNAs play an oncogenic role in ccRCC, whereas knockdown of EMX2OS increased proliferation, migration, and invasion, suggesting that EMX2OS plays a tumor-suppressive role in ccRCC. This evidence concerns the gene EMX2OS and nonpapillary renal cell carcinoma.