We collected 101 published signatures (Supplementary Table 7) involving various biological characteristics, including cuproptosis, ferroptosis, autophagy, pyroptosis, necroptosis, fatty acid metabolism, glutamine metabolism, immune checkpoint, Tumor-infiltrated CD8+ T Cell, IFN-γ response, oxidative stress, ERBB signaling pathway, basement membrane, and alternative splicing. This evidence concerns the gene CD8A and neoplasm.