CD8A and neoplasm: A microvesicle-inspired oxygen-delivering polyfluorocarbon nanosystem loading DiIC18(5) and halofuginone (M-FDH) produced a 10.98-fold enhancement of tumor oxygenation and caused efficient production of ROS upon radiation, which resulted in over 90% elimination of CAFs, enhancement of CD8+T cells, and elimination of suppressive immune cells (141).