KLF3 and acute lymphoblastic leukemia: By integrating the TGCA and GTEx databases, we found that KLF3 mRNA was significantly upregulated in 14 types of tumors (ALL, CHOL, COAD, COADREAD, ESCA, GBM, GBMLGG, LAML, LGG, LIHC, PAAD, STAD, STES, and WT; all p<0.01), while it was significantly downregulated in 13 types of tumors (BLCA, BRCA, KICH, KIPAN, KIRC, KIRP, LUAD, OV, READ, SKCM, THCA, UCEC, and UCS; all p < 0.01), compared with normal tissues (Figure 1A).