Other genes that had a higher expression in GCA were PLAC8, previously found to upregulated on activated monocytes (21), PIM1 which is related to a protein regulating proinflammatory cytokine responses in synoviocytes (22) and PHLDA1, which was recently found to be related to TLR4 activity (23). The gene discussed is TLR4; the disease is temporal arteritis.