The HDR syndrome (OMIM 146255), also known as Barakat syndrome, is a rare autosomal dominant disorder characterised by Hypoparathyroidism (H), Deafness (D), and Renal dysplasia (R), and is caused by germline mutations of the GATA3 gene (1, 2). The gene discussed is GATA3; the disease is Hypoparathyroidism - deafness - renal disease.