Results showed that CD27-AS1, SNHG16, ELFN1-AS1, LINC01011, LINC02474, SNHG16, AP001505.1, and AC068580.3 expressions were significantly higher, while PINK-AS1, LINC02381, AC015726.1, and AL450326.1 were significantly lower in the COAD tissues than in the normal tissues. This evidence concerns the gene CD27 and colon adenocarcinoma.