The results showed that AD patients had higher levels of activated CD8 T cell, CD56bright natural killer cell, CD56dim natural killer cell, central memory CD8 T cell, effector memory CD8 T cell, immature B cell, immature dendritic cell, mast cell, MDSC, natural killer cell, natural killer T cell and plasmacytoid dendritic cell, while gamma delta T cell and Type 1 T helper cell did not show significant differences (Figure 3E). This evidence concerns the gene CD8A and Alzheimer disease.