CXCL1 and infection: The most well-known function of IL-17 is its ability to initiate an inflammatory response inducing neutrophil-specific chemokines [(CXCL1, CXCL2, CXCL5, and IL-8) that attract neutrophils from the bloodstream to sites of infection, the expression of adhesion molecules to facilitate the firm attachment and extravasation [10], and granulocyte colony-stimulating factors (G-CSF) that promotes neutrophil generation and migration to the site of infection at surfaces of the skin and mucosa [55].