INS and coronary artery disorder: The results of this study showed that the addition of probiotics or synbiotics to conventional medications for CAD reduced the levels of LDL-C [WMD −9.13 (−13.17, −5.09)], FPG [WMD −13.60 (−23.57, −3.62)], insulin [WMD −3.39 (−4.92, −1.86)], LPS [SMD −0.55 (−1.19, −0.09)], hs-CRP [SMD −0.60 (−0.83, −0.37)], and TMAO [SMD −0.58 (−0.98, −0.18)] and increased the levels of HDL-C [WMD 1.94 (0.32, 3.57)] and NO [WMD 5.38 (3.23, 7.54)] but did not affect TG [WMD −13.41 (−28.03, 1.21)], SBP [WMD −0.88 (−3.72, 1.96)], and DBP [WMD −0.21 (−2.19, 1.76)].