RYR2 and catecholaminergic polymorphic ventricular tachycardia: Results showed two novel variants at RYR2 locus, including one de-novo variant (c13892A > T; p.D4631V) in a CPVT patient and a rare novel variant (c5428G > C; p.V1810l) of significance in a patient with idiopathic ventricular tachycardia (75).