only one preoperative study reported recurrent myocardial infarction, stroke, IL-6, adverse events, and mortality events among all the included indicators, two preoperative studies evaluated hs-CRP; five postoperative studies reported adverse events, three studies reported stroke, mortality, and myocardial infarction, two studies reported stent thrombosis, and two studies examined hs-CRP, but only one analyzed IL-6 and ISR; mortality events occurred in three pre-and postoperatively studies, two reported adverse events, only one assessed stroke, and hs-CRP, and one reported ISR. This evidence concerns the gene IL6 and Stroke.