To complete glycolysis in cancer cells, glucose transporter (GLUT) and such enzymes as hexokinase (HK), phosphofructokinase (PFK), pyruvate kinase (PK), lactate dehydrogenase A (LDHA), enolase 1 (Recombinant), Human Enolase-1, ENO1, pyruvate dehydrogenase kinases (PDKs) work jointly to meet the enormous demand for energy. The gene discussed is LDHA; the disease is cancer.