The IVW estimates indicated that there is no statistically significant association between genetically determined resistin concentrations and risk of CRC using GECCO data (ORper SD of resistin, 1.01; 95% CI 0.96, 1.07; p = 0.67) or using FinnGen data (ORper SD of resistin, 1.00; 95% CI 0.82, 1.22; p = 0.99) or all data sources combined (ORper SD of resistin, 1.01; 95% CI 0.96, 1.06; p = 0.67) (Fig. 2, Supplementary Fig. 2). Here, RETN is linked to colorectal carcinoma.