RETN and colorectal carcinoma: Alternatively, in our current MR study we were able to investigate the association between genetically determined lifelong differences in circulating resistin in relation to CRC risk (Burgess et al. 2019) that was less susceptible to attenuation due to within-individual variations of resistin levels (Pierce and VanderWeele 2012) and circumvented reverse causation (Burgess et al. 2019).