The highest number of DEGs occurred in KEGG metabolic pathways (68 genes), followed by pathways of neurodegeneration (15 genes), MAPK signaling (14 genes), axon guidance (14 genes), Alzheimer’s disease (14 genes), cancer (12 genes), amyotrophic lateral sclerosis (12 genes), Huntington disease (12 genes), and PI3K-Akt signaling (10 genes). Here, AKT1 is linked to early-onset autosomal dominant Alzheimer disease.