Immunohistochemical staining of FGFR1 and Ki67 in MCL patients (n = 31) (Our cohort; Supplementary Table 3) uniformly treated with front-line R/CHOP and normal lymph node controls were performed and analyzed by a hematopathologist (Fig. 1E) for validation. The gene discussed is DDIT3; the disease is mantle cell lymphoma.