NLRP3 and rheumatoid arthritis: NLRP3 has been linked to the pathophysiology of rheumatoid arthritis (RA)16,17, systemic lupus erythematosus (SLE)18–20, gout17,21, nonalcoholic steatohepatitis (NASH)22–25, Alzheimer’s disease (AD)17,26,27, multiple sclerosis (MS)28–33, atherosclerosis17,34,35 and asthma and airway inflammation36–38.