CD8A and Increased total eosinophil count: Compared to the OVA sensitized and OVA challenged (OVA/OVA) CD8α−/− mice, the recipients of the iTreg cells showed a significant increase in AHR, airway neutrophilia and eosinophilia and a visible increase in submucosal inflammatory cell infiltration (Fig. 5B,C,F, Supplementary Fig. 4A).