The FTO research had been the recent discovery of the first N6-methyladenosine (m6A) ribonucleic acid demethylase, which has been linked to depression, and its gene polymorphisms show a positive correlation with depression subtypes, such as atypical depression characterized by increased appetite, sleepiness and weight gain by regulating RNA (Ribonucleic acid) processing [54, 55]. Here, FTO is linked to major depressive disorder.