The respective frequencies of TERT promoter mutations in UC, adenocarcinoma, micropapillary variants, and plasmacytoid variants are 52%, 57%, 100%, and 60%, although such mutations are usually absent from potentially benign mimics (e.g., von Brunn nests, cystitis cystica, and nephrogenic adenoma) and metastatic carcinoma [26, 27]. This evidence concerns the gene TERT and metastatic carcinoma.