CD8A and infection: B cells (p = 0.015), NK T cells (p = 0.002), CD8- T cells (p = 0.0002), and CD8 + T cells (p < 0.0001) were all significantly decreased in the severe infection group compared to healthy controls and moderate infection (B cells: p = 0.002; NK T cells: p = 0.020; CD8- T cells: p = 0.030; CD8 + T cells: p = 0.009) (Fig. 2A).