Also, while rTMS was reported to enhance serum levels of BDNF and cortical excitability (Zhao et al., 2020, 2021), this may not be related to genetic variants, since very similar facilitation of cortical excitability by rTMS was found regardless of BDNF Val/Met polymorphisms in healthy subjects and stroke patients (Hwang et al., 2015; Uhm et al., 2015). This evidence concerns the gene BDNF and Stroke.