Considering specifically vascular endothelial localization of FSCN1 in retina and choroid, CD31-enriched scRNA-seq data (GEO: #GSE135922 [50]) of choroidal tissues from donors with wet age-related macular degeneration (wAMD), donors with dry age-related macular degeneration (dAMD) and donors without AMD (NORM) were re-analyzed with higher endothelial cell abundance [50]. Here, PECAM1 is linked to wet macular degeneration.